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Oxidative stress and diabetes: antioxidative strategies

Pengju Zhang, Tao Li, Xingyun Wu, Edouard C. Nice, Canhua Huang, Yuanyuan Zhang

Frontiers of Medicine 2020, Volume 14, Issue 5, Pages 583-600 doi: 10.1007/s11684-019-0729-1

Abstract: There are a number of potential problems in the clinical application of antioxidant therapies includingNovel antioxidant delivery systems may overcome pharmacokinetic and stability problem and improve the

Keywords： diabetes oxidative stress redox modification antioxidative therapy novel antioxidant delivery

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EMBRYOGENESIS ABUNDANT FAMILY GENE FROM PONCIRUS TRIFOLIATA, CONFERS ENHANCED DROUGHT TOLERANCE BY ENHANCING ANTIOXIDANT

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: In addition, transgenic plants had much higher expression levels of three antioxidant enzyme genes (CATthis study demonstrates that PtrLEA7 can confer enhanced drought tolerance partially via enhancing antioxidant

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Polyamines and antioxidant defense system are associated with cold tolerance in centipedegrass

Jingjing CHEN, Junyang FANG, Zhenfei GUO, Shaoyun LU

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 1, Pages 129-138 doi: 10.15302/J-FASE-2017197

Abstract: Exogenous Put or Spd increased antioxidant enzyme activities and chilling tolerance.

Keywords： antioxidants centipedegrass chilling photosynthesis polyamines

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OVEREXPRESSION OF

Tonglu WEI, Dalong GUO, Jihong LIU

Frontiers of Agricultural Science and Engineering Pages 236-246 doi: 10.15302/J-FASE-2020368

Keywords： abiotic stress antioxidant drought late embryogenesis abundant Poncirus trifoliata

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Biodegradable polymethacrylic acid grafted psyllium for controlled drug delivery systems

Ranvijay KUMAR, Kaushlendra SHARMA

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1, Pages 116-122 doi: 10.1007/s11705-013-1310-0

Abstract: Polymethacrylic acid (PMA) was synthesized on the backbone of psyllium (Psy) by a microwave assisted method to prepare polymeric grafted materials designated as (Psy- -PMA). Various grades of Psy- -PMA were prepared by changing the degree of grafting from 35%–58% and the materials were then made into tablets. Swelling and biodegradability studies of the tablets were carried out. Acetyl salicylic acid was incorporated in the various Psy- -PMA samples and tablets were prepared to study the in vitro drug release in acidic (pH= 4), neutral (pH= 7), and basic (pH= 9) media. In the acidic medium, the swelling was more than 1300%. In addition, the biodegradable Psy- -PMA had the highest drug release in the acidic medium. This may be attributed to Fickian diffusion since the drug and the medium in which it was released have the same acidic nature.

Keywords： psyllium acetyl salicylic acid in-vitro drug release swelling biodegradation

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Engineering platelet-mimicking drug delivery vehicles

Quanyin Hu, Hunter N. Bomba, Zhen Gu

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4, Pages 624-632 doi: 10.1007/s11705-017-1614-6

Abstract: Platelets dynamically participate in various physiological processes, including wound repair, bacterial clearance, immune response, and tumor metastasis. Recreating the specific biological features of platelets by mimicking the structure of the platelet or translocating the platelet membrane to synthetic particles holds great promise in disease treatment. This review highlights recent advancements made in the platelet-mimicking strategies. The future opportunities and translational challenges are also discussed.

Keywords： drug delivery platelets nanomedicine bio-inspired biomimetic

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Gene delivery into isolated

Nan Zheng, Ziyuan Song, Yang Liu, Lichen Yin, Jianjun Cheng

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4, Pages 521-528 doi: 10.1007/s11705-017-1612-8

Abstract: The application of gene delivery materials has been mainly focused on mammalian cells while rarely extendedThis study therefore widens the utilities of helical polypeptide as a unique category of gene deliverymaterials, and may find their promising applications toward plant gene delivery.

Keywords： α-helical polypeptide plant gene delivery protoplast intact leaves transfection

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Introduction to the special issue of the 2009 International Symposium on Crystal Engineering & Drug Delivery

Zhijian CHEN, Wei LI,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 1, Pages 1-1 doi: 10.1007/s11705-009-0306-2

Abstract:

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Controlled drug delivery systems: the next 30 years

Yeonhee YUN,Byung Kook LEE,Kinam PARK

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 3, Pages 276-279 doi: 10.1007/s11705-014-1426-x

Abstract: The drug delivery scientists need to reexamine the advances made during the past 60 years, analyze ourabilities, and design the future technologies that will propel us to achieve the next level of drug deliveryEffective drug delivery systems can be developed by overcoming formulation barriers and/or biologicalso that they can be overcome by engineering manipulation of the drug delivery systems.The new generation of drug delivery scientists needs to be aware of the successes and limitations of

Keywords： drug delivery history formulation barriers nanotechnology clinical product

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Bioorthogonal chemistry based on-demand drug delivery system in cancer therapy

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 4, Pages 483-489 doi: 10.1007/s11705-022-2227-2

Abstract: Benefiting from the advantage of taking place in biological environments without interfering with an innate biochemical process, the bioorthogonal reaction that commonly contains the “bond formation” and “bond cleavage” system has been widely used in targeted therapy for a variety of tumors. Herein, several prominent cases based on the bioorthogonal reaction that tailoring the metabolic glycoengineering tactics to modified cells for cancer immunotherapy, and the innovative tactics for reducing the metal ions’ toxic and side effects with microneedle patches will be highlighted. Based on these applications, the complexities, potential pitfalls, and opportunities of bioorthogonal chemistry in future cancer therapy will be evaluated.

Keywords： bioorthogonal reaction cancer therapy metabolic glycoengineering bioorthogonal catalytic patch

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Effect of the new maternity insurance scheme on medical expenditures for caesarean delivery in Wuxi,

Chun Chen,Zhihong Cheng,Ping Jiang,Mei Sun,Qi Zhang,Jun Lv

Frontiers of Medicine 2016, Volume 10, Issue 4, Pages 473-480 doi: 10.1007/s11684-016-0479-

Abstract: We used 6547 caesarean delivery case records from a teaching tertiary-level general public hospital locatedmodels to compare the mean medical expenditures between insured and uninsured women undergoing caesarean deliveryThese findings indicated the scheme’s effectiveness in minimizing caesarean delivery expenditures

Keywords： maternity insurance scheme financial incentive caesarean delivery medical expenditure China

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Economic analysis of a hybrid solar-fuel cell power delivery system using tuned genetic algorithm

Trina SOM, Niladri CHAKRABORTY

Frontiers in Energy 2012, Volume 6, Issue 1, Pages 12-20 doi: 10.1007/s11708-012-0172-3

Abstract: evaluation of a network of distributed energy resources (DERs) comprising a microgrid structure of power deliveryfor optimal power operation pertaining to minimum cost have been made for two cases in Indian power delivery

Keywords： distributed energy resources (DERs) microgrid tuned genetic algorithm (TGA)

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Antioxidant and antitumor effects and immunomodulatory activities of crude and purified polyphenol extract

Xiaohong Kou,Lihua Han,Xingyuan Li,Zhaohui Xue,Fengjuan Zhou

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 1, Pages 108-119 doi: 10.1007/s11705-016-1553-7

Abstract: The antioxidant and antitumor effects as well as the immunomodulatory activities of crude and purifiedThe antioxidant and antitumor effects of the polyphenol extract were measured both and , and theirassays demonstrated that blueberry purified polyphenol extract (BBPP) exhibited higher antioxidant activitiesThese results indicate that BBCP has significant antioxidant and antitumor activities and that it can

Keywords： crude polyphenol extract purified polyphenol extract blueberry antioxidant antitumor immunity

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Inhibition of NO emission by adding antioxidant mixture in

A. PRABU,R. B. ANAND

Frontiers in Energy 2015, Volume 9, Issue 2, Pages 238-245 doi: 10.1007/s11708-015-0356-8

Abstract: In this paper, the effect of adding an antioxidant mixture in biodiesel as fuel, in a single cylinderThe comparison showed that NO emission was reduced drastically for the test fuels with the antioxidantThe maximum reduction of 10% of NO emission was observed for the antioxidant mixture in neat biodiesel

Keywords： NO emission antioxidants Succinimide N N-dimethyl-p-phenylenediamine-dihydrochloride N-phenyl-p-phenylenediamine

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Zeolitic imidazolate framework-8 (ZIF-8) for drug delivery: A critical review

Simin Feng, Xiaoli Zhang, Dunyun Shi, Zheng Wang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2, Pages 221-237 doi: 10.1007/s11705-020-1927-8

Abstract: focuses on the recent development of ZIF-8 synthesis methods and its promising applications in drug deliveryThe potential risks of using ZIF-8 for drug delivery are also summarized.

Keywords： zeolitic imidazolate framework-8 (ZIF-8) synthesis methods applications drug delivery